How long is Dr. Mario 64?

Dr. Mario 64 takes about 1h 59m to beat the main story, or around 3h 17m with extras.

How long does it take to 100% Dr. Mario 64?

A completionist run of Dr. Mario 64 takes about 4h 51m.

68Meta Score

Dr. Mario 64

Puzzle

Developer: Nintendo IRD|Publisher: iQue, Gradiente, Nintendo

Playtime

Updated community averages based on player submissions.

Main Story

1h 59m

Main + Extra

3h 17m

Completionist

4h 51m

Media

2 videos + 4 screenshots

Links

Wiki Wikipedia Twitch

About This Game

The flu season has come about, and it's Dr. Mario's duty to use his Megavitamins to heal the people of the land. However, Wario, wanting to have the fame that Dr. Mario has, attempts to steal the Megavitamins, but to no avail. Afterwards, Mad Scienstein and Rudy the Clown (from Wario Land 3) steal the Megavitamins, and both Dr. Mario and Wario give chase.

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Last updated Mar 7, 2026